Listen to a podcast Adversce Childhood Experiences and the Risk of Premature Mortality.
To explore the effect that childhood trauma could have on life span, Kaiser Permanente mailed questionnaires to adults who were 18 years and older, and who had visited the Kaiser clinic in San Diego from 1995 to 1997. Overall, the study subjects were middle-class and had good health coverage. Of those surveyed, 75 percent were white, 11 percent Latino, 7 percent Asian, and 5 percent African-American. They’re educated: 75 percent attended college and 40 percent have a basic or higher college education. When they filled out the questionnaire, their average age was 57. Most of them had jobs. Half were women, half were men.
The participants were asked about their exposure to eight categories of abuse or dysfunction based on previous Kaiser studies. One third of the 17,337 participants who replied to the questionnaires had an ACE score of zero, meaning they had not been exposed to any of the eight types of abuse or household dysfunction. The majority of the remaining responders registered a score of between one and four, whereas about 8 percent of the scoring participants were rated five, and roughly three percent, six to eight.
During the next decade, the study authors, kept records of which of the 17,337 participants passed away by matching identifying information such as Social Security numbers from the questionnaire with data from the National Death Index. In total 1,539 of the participants died during the follow-up period. When the increased number of deaths in those subjects with an ACE score of six or greater was compared with the control group, their mortality risk was 1.5 times higher than for people whose childhoods had been free of all eight types of abuse. They lost about 20 years from their lives, living to 60.6 years on average, whereas the average age of death for the control group was 79.1.
It is unclear why the authors saw more death ages during the 10-year period only for the group with an ACE score of six or greater. Previous studies by these authors found that the risk of chronic illnesses, such as heart disease, lung disease and cancer, was greater only for people with these high ACE scores. In contrast, the risk of substance abuse and suicide increased stepwise from low to high scores. The authors found that ACE-related health risks, namely mental illness, social problems and prescription medication use, accounted for about 30 percent of the 50 percent greater risk of death seen in this population. "As would be expected, the documented ACE-related conditions among participants appear to account for some, although not all, of the increased risk of premature death observed in the current study," wrote David Brown, an epidemiologist at the U.S. Centers for Disease Control and Prevention (CDC), and lead author of the study.


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